Body Systems

High Blood Pressure4 Results found

Telmisartan vs. Perindopril in Hypertensive Mild-Moderate Alzheimer's Disease Patients (SARTAN-AD)

The purpose of this project is to conduct a proof of concept study in patients with probable Alzheimer's Disease who have mild to moderate hypertension, in order to determine if there is less global brain atrophy over one year, as measured by ventricular enlargement as a primary outcome measure,

Principal Investigator 
Ging-Yuek Robin Hsiung
Body Locations and Systems 
Alzheimer's Disease, High Blood Pressure
Area 
Vancouver
Age 
55 and above

Hypertension (TRITON)…

The objective of this clinical trial is to compare the efficacy and safety of an initial triple oral treatment regimen (macitentan, tadalafil, selexipag) versus an initial dual oral treatment regimen (macitentan, tadalafil, placebo) in newly diagnosed, treatment-naïve patients with pulmonary arte

Principal Investigator 
John Swiston
Body Locations and Systems 
High Blood Pressure, Pulmonary Hypertension
Area 
Vancouver
Age 
18-75

Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST

This study assesses the safety and efficacy of bardoxolone methyl relative to placebo in patients with connective tissue disease-associated pulmonary arterial hypertension to determine the recommended dose range and evaluate the change from baseline in 6-minute walk distance (6MWD) following 24 w

Principal Investigator 
John Swiston
Body Locations and Systems 
High Blood Pressure
Area 
Vancouver
Age 
18-75