The Hip Health Information Project (HHIP) is a study investigating the experiences and perceptions of pre-surgical education to prepare patients with osteoarthritis (OA) of the hip for hip replacement surgery.

The purpose of this study is to assess clinicians' experiences and perceptions of prehabilitation education and determine necessary measures for improving educational programming based on the perspective of clinicians who are working with osteoarthritis hip or knee patients.

Knee osteoarthritis is one of the most prevalent and costliest chronic health conditions affecting Canadians.  In the absence of a cure, identification of effective and inexpensive treatment strategies is paramount.  Shoe-worn insoles (orthotics) may play a role in this regard.  However, outcomes

The specific question the investigators will seek to answer is: can the Reamer Irrigator Aspirator (RIA) provide a bone graft source for the treatment of nonunions that is equally effective to Autogenous Iliac Crest Bone Graft (AICBG) while resulting in a decreased amount of post-operative pain a

To determine if Far Cortical Locking screws increase fracture healing rates at 3 months in Closed Distal Femur Fractures in adults when compared to standard locking screw constructs.

Fracture healing at 3 months will be assessed via x-ray and clinical assessment of the fracture.

The purpose of this study is to better understand the expectations patients have of a total knee replacement, and to compare the outpatient rehabilitation system in Canada with the inpatient rehabilitation system in Germany for the purpose of cost analysis and rehabilitation outcomes of patients

The purpose of this study is to evaluate the safety and efficacy of daily subcutaneous injections of elamipretide in subjects with primary mitochondrial myopathy.

The overall purpose of this study is to assess the feasibility of a cross-country non-inferiority randomized controlled trial (RCT) comparing midline sparing decompression alone (MSDA) to usual care (decompression with fusion).

HIP ATTACK is an international randomized controlled trial of 1200 patients with a hip fracture that requires a surgical intervention.

Knee osteoarthritis (OA) is a costly health condition affecting more than 10% of Canadian adults. Excessive and unbalanced loads passing through the knee joint have been implicated in the progression of OA.