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Acute Myeloid Leukemia4 Results found

Studies recruiting participants:

(QuANTUM-R): An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects Who Are FLT3-ITD Positive

The primary objective of the study is to determine whether quizartinib monotherapy prolongs overall survival (OS) compared to salvage chemotherapy in subjects with FMS-like tyrosine kinase 3 - Internal Tandem Duplication (FLT3-ITD) positive AML who are refractory to or have relapsed within 6 mont

Recruiting

Principal Investigator

Donna E. Hogge

Body Locations and Systems

Leukemia

Area

Vancouver

Age

18 and above

Ibrutinib in Combination With Corticosteroids Versus Placebo in Combination With Corticosteroids in Subjects With New Onset Chronic Graft Versus Host…

To evaluate the safety and efficacy of ibrutinib in combination with prednisone in subjects with newly diagnosed moderate to severe cGVHD.

Recruiting

Principal Investigator

Raewyn Broady

Body Locations and Systems

Leukemia, Blood

Area

Vancouver

Age

12 and above

Closed for recruitment:

Study of Vosaroxin or Placebo in Combination With Cytarabine in Patients With First Relapsed or Refractory Acute Myeloid Leukemia (AML)…

This study will compare the overall survival (OS) between treatment groups of patients treated with vosaroxin and cytarabine versus patients treated with placebo and cytarabine.

Closed for Recruitment

Principal Investigator

Donna E. Hogge

Body Locations and Systems

Leukemia

Area

Vancouver

Age

18 and above

Phase III Study of CPX-351 Versus 7+3 in Patients 60-75 Years Old With Untreated High Risk (Secondary) Acute Myeloid Leukemia…

To confirm the efficacy of CPX-351 compared to 7+3 as first line therapy in elderly patients (60-75 yrs) with high risk (secondary) Acute Myeloid Leukemia. The primary efficacy endpoint will be overall survival.

Closed for Recruitment

Principal Investigator

Donna E. Hogge

Body Locations and Systems

Leukemia

Area

Vancouver

Age

60-75

Body Systems

Arteries (12)

Blood (32)

Heart (52)

Bones (7)

Hip, Leg and Foot (8)

Joints (11)

Muscles (1)

Shoulder, Arm and Hand (1)

Spine (4)

Brain (98)

Nerves (1)

Spinal Cord (6)

Large Intestine (14)

Liver (22)

Small Intestine (13)

Ear (1)

Nose (3)

Throat (1)

Pancreas (14)

Thyroid (1)

Eye Disorders (15)

HIV (1)

Immune System and Disorders (6)

Bladder (3)

Kidney (23)

Lungs (29)

Men's Health (30)

Women's Health (21)

Mouth (1)

Skin Conditions (17)

Disorders and Conditions

Diagnosis and Therapy

Acute Myeloid Leukemia4 Results found

Studies recruiting participants:

(QuANTUM-R): An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects Who Are FLT3-ITD Positive

Ibrutinib in Combination With Corticosteroids Versus Placebo in Combination With Corticosteroids in Subjects With New Onset Chronic Graft Versus Host…

Closed for recruitment:

Study of Vosaroxin or Placebo in Combination With Cytarabine in Patients With First Relapsed or Refractory Acute Myeloid Leukemia (AML)…

Phase III Study of CPX-351 Versus 7+3 in Patients 60-75 Years Old With Untreated High Risk (Secondary) Acute Myeloid Leukemia…

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