A Pilot Study Comparing the Use of Low-target Versus Conventional Target Advagraf (Astellas)While the incidence of acute rejection and early graft loss have improved dramatically with the advent of newer immunosuppressant medications, improvements in long-term patient and allograft survival after kidney transplantation have not been achieved. Principal Investigator John GillBody Locations and Systems Kidney TransplantationArea VancouverAge 19 and above
Peripheral Diabetic Retinopathy (DR) Lesions on Ultrawide-field Fundus Images and Risk of DR Worsening Over Time To determine the association between peripheral diabetic retinopathy lesions and the likelihood of diabetic retinopathy worsening or improving over time. Principal Investigator David MaberleyBody Locations and Systems Diabetic Eye Problems, Diabetes - Type 1, Diabetes - Type 2Area VancouverAge 18 and above
Insulin Therapy and Falls Due to Orthostatic HypotensionIn the proposed study, the investigators examine in older adults with Type 2 diabetes the impact of beginning insulin therapy on the orthostatic drop in blood pressure as well as the response of arterial blood pressure and Doppler measures of cerebral blood flow during upright tilt. Principal Investigator Kenneth MaddenBody Locations and Systems Low Blood PressureArea VancouverAge 65 and above
Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease…This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study in overweight and obese subjects with CV disease and/or multiple CV risk factors. Principal Investigator Graham WongBody Locations and Systems Diabetes - Type 2, Coronary Artery DiseaseArea VancouverAge 40 and above
