The purpose of this study is to evaluate the effectiveness and tolerability of an oral study drug in individuals who experience upper limb essential tremor. Eligible participants will be randomly assigned to three different doses of the study drug or to a placebo.
The purpose of this study is to look at the link between regions of brain activity and impulsivity and to look at a non-invasive intervention called repetitive transcranial magnetic stimulation (rTMS) to help reduce the risk of impulsive behaviours.
The purpose of this study is to investigate changes in the brain in people affected by Parkinson’s disease using PET and fMRI imaging.
The purpose of this study is to investigate whether Electrical Vestibular Stimulation (EVS) can lessen orthostatic hypotension in Parkinson’s disease patients. We aim to determine if individual precision-designed EVS stimulus can be optimized for improvements in hypotension.
The purpose of this study is to assess the efficacy of two drug treatments measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS.
The purpose of this study is to investigate the impact of genetic and non-genetic risk factors for Alzheimer’s disease (AD), evaluate differential
effects of sex on AD risk, and predict diagnosis of AD using dementia risk scores derived from genetic and nongenetic risk factors.
The purpose of this study is to evaluate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) to treat depression.
The purpose of this study is to test the safety and efficacy of TAK-079, a medicine to help people with generalized myasthenia gravis.
The purpose of this study is to is to examine the effects of 12 weeks of high intensity interval training on the cognitive health of perimenopausal woman.
The purpose of this study is to test the feasibility of Magnetic Seizure Therapy for treating depression in patients diagnosed with Parkinson's Disease.
A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (O'HAND)
The purpose of this study is to evaluate the efficacy and safety of ocrelizumab ( Ocrevus®) compared with placebo in participants with primary progressive multiple sclerosis (PPMS).
A Feasibility Study of Adherence to Light Therapy for Maintenance Treatment of Major Depressive Disorder
The purpose of this study is to explore the use of bright light therapy as maintenance treatment for depression to determine if it is
The purpose of this study is examine the use of low concentration capsaicin (the active ingredient in chili peppers) cream applied for extended periods of time to help manage neuropathic pain after spinal cord injury.
The purpose of this study is to evaluate the safety and effectiveness of non-invasive electrical spinal stimulation for restoration of upper extremity function.
The purpose of this study is to determine ways to meet the social needs related to loneliness and isolation in seniors with dementia while examing barriers and successes surrounding the use of a robot-assisted, virtual care solution within care settings.
This project is investigating the immediate and long-term effects of non-invasive transcutaneous spinal cord stimulation (TCSCS) on bladder, bowel, and sexual function in people with SCI.
Motor and Autonomic Concomitant Health Improvements With Neuromodulation and Exoskeleton Training: A RCT in Individuals With SCI (MACHINE)
This project aims to assess the efficacy of activity-based therapy in combination with non-invasive transcutaneous spinal cord stimulation to promote the recovery of motor function, bowel function, bladder function, sexual function and quality of life in individuals with spinal cord injury.
The purpose of this study is to evaluate the use of an oral multi-strain probiotic in the treatment of anxiety in individuals with Parkinson's Disease.
The purpose of this study is to evaluate the efficacy and safety of the drug pridopidine in patients with early stage manifest Huntington Disease.