Body Systems

COPD7 Results found

Studies recruiting participants:

COPD Originates in Polluted Air (COPA)

The investigators are investigating the effects of traffic-related diesel exhaust on lung function and the immune system in those at risk for COPD. The individual will be exposed to either filtered air (FA) or carefully controlled levels of diesel exhaust (DE) in our exposure chamber.

Recruiting
Principal Investigator 
Christopher Carlsten
Body Locations and Systems 
COPD
Area 
Vancouver
Age 
40-75

Tezepelumab COPD Exacerbation Study (COURSE)

The purpose of this study is to explore the efficacy and safety of tezepelumab in adults with moderate to very severe chronic obstructive pulmonary disease (COPD).

Recruiting
Principal Investigator 
Mark FitzGerald
Body Locations and Systems 
COPD
Area 
Vancouver
Age 
40-80

Closed for recruitment:

Comparing the Efficacy of Tiotropium + Olodaterol (5/5 µg) Fixed Dose Combination (FDC) Over Tiotropium 5µg in Reducing Moderate to…

The overall objective is to assess the effect of once daily tiotropium + olodaterol fixed dose combination compared to 5 µg tiotropium (both delivered with the Respimat® inhaler) on moderate to severe COPD exacerbation in patients with severe to very severe COPD

Closed for Recruitment
Principal Investigator 
Jeremy D. Road
Body Locations and Systems 
COPD
Area 
Vancouver
Age 
40 and above

A Study to Evaluate the Safety, Efficacy and Changes in Induced Sputum and Blood Biomarkers Following Daily Repeat Doses of…

The purpose of this study is to evaluate specific alterations in immune cell mechanisms related to neutrophil function as detected by PI3Kdelta-dependent changes in messenger ribonucleic acid (mRNA) extracted from induced sputum in patients experiencing an exacerbation of COPD, with or without tr

Closed for Recruitment
Principal Investigator 
Mark FitzGerald
Body Locations and Systems 
COPD
Area 
Vancouver
Age 
40-80