Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial (PROSPECT)Probiotics are commercially available live bacteria thought to have health benefits when ingested. Principal Investigator Peter DodekBody Locations and Systems Pneumonia, Clostridium Difficile InfectionsArea VancouverAge 18 and above
Study of a Candidate Clostridium Difficile Toxoid Vaccine (Cdiffense) in Subjects at Risk for C. Difficile InfectionThe aim of this study is to evaluate the efficacy of the candidate Clostridium difficile (C. difficile) vaccine to prevent primary symptomatic C. difficile infection (CDI) in subjects a risk for CDI where there is a substantial unmet medical need. Principal Investigator Theodore SteinerBody Locations and Systems Clostridium Difficile InfectionsArea VancouverAge 50 and above
Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCHCD2)This is the first prospective, multi-center, double-blinded, randomized controlled study of a microbiota suspension derived from intestinal microbes. Patients who have had at least two recurrences of C. Principal Investigator Theodore SteinerBody Locations and Systems Clostridium Difficile InfectionsArea VancouverAge 18 and above
Multi-Centre Trial of Fresh vs. Frozen-and-Thawed HBT(Fecal Transplant)for Recurrent CDIThe goal of this study is to determine the outcome of patients with recurrent CDI treated with fresh HBT versus frozen-and-thawed HBT in a randomized controlled trial. Principal Investigator Theodore SteinerBody Locations and Systems Clostridium Difficile InfectionsArea VancouverAge 18 and above
A Prospective Trial of Frozen-and-Thawed Fecal Microbiota Transplantation for Recurrent Clostridium Difficile InfectionThe primary goal of this proposal is to study the outcome of patients with recurrent Clostridium Difficile Infection (CDI) treated with frozen Fecal Microbiota Transplantation (FMT) in an open-labelled controlled trial. Principal Investigator Theodore SteinerBody Locations and Systems Clostridium Difficile InfectionsArea VancouverAge 18 and above
Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated DiarrheaThis clinical study is conducted to assess the efficacy of cadazolid compared to vancomycin in subjects with Clostridium difficile-associated diarrhea (CDAD). Principal Investigator Theodore SteinerBody Locations and Systems Clostridium Difficile InfectionsArea VancouverAge 18 and above
