This is a randomized, double-blind, placebo-controlled, multicentre, parallel-group study to assess the cognitive effects of lurasidone in bipolar I and II patients (manic depression) who are in remission from an episode.

In this study, we will examine how sexual identity (asexuality and heterosexuality) and sexual difficulties (i.e. clinically low desire) are related to the cognitive processing of sexual and non-sexual information.

The purpose of this study is to determine if treatment with androgen deprivation therapy (ADT) plus apalutamide before and after radical prostatectomy in participants with high-risk localized or locally advanced prostate cancer results in an improvement in pathological complete response (pCR) rat

The goal of the current study is to determine the prevalence, rate, and types of pregnancy complications and early life events that may be associated with the emergence of psychosis and related metabolic disorder in patients with schizophrenia spectrum disorders.

The purpose of the study is to learn how women with and without sexual difficulties respond to videos and pictures, some of which contain erotic material.  More specifically, we aim to understand the neurocognitive correlates of sexual arousal and desire, including attention to sexual cues, and p

The purpose of this study is to evaluate the safety and tolerability of AMG 160; a half-life extended (HLE) bispecific T-cell engager (BiTE®) antibody construct, alone and in combination with pembrolizumab in subjects with metastatic castration-resistant prostate cancer.

We would like to explore different aspects of sexual identity among individuals who self-identify as asexual, bisexual, gay, or heterosexual.

Recruitment Poster

The BREAST study aims to support female breast cancer survivors with the changes that breast cancer treatment can bring to their sexual lives. We will compare two effective treatments - a mindfullness-based treatment and sex education - in addressing difficulties with sexual desire, sexual distre

One in eight men will be diagnosed with prostate cancer in their lifetime, and up to 90% of men who receive treatment will experience changes to their sexual functioning and their intimate lives.  We are interested in evaluating different treatment options for improving intimacy in couples after

The investigators aim to evaluate the feasibility of a larger clinical trial assessing an exercise program during the "teachable moment" in patients with prostate cancer and measuring its effect on tumor apoptosis signaling, lipogenesis and steroidogenesis.

Indigenous women's wellness has multigenerational impacts on the health of indigenous communities.  VCH Aboriginal Health has identified indigenous women's wellness as a priority, and this research will bring the voice of indigenous women into VCH policy and program development.  These goals incl

The purpose of this study is to determine if the addition of JNJ-56021927 to ADT provides superior efficacy in improving radiographic progression-free survival (rPFS) or overall survival (OS) for participants with low volume mHSPC.

99mTc-MIP-1404 is a radioactive diagnostic imaging agent indicated for imaging men with newly diagnosed prostate cancer whose biopsy indicates a histopathologic Gleason grade of ≤ 3+4 severity and / or are candidates for active surveillance, but have planned to undergo radical prostatectomy.

Prostate Cancer Survivorship 360º is a collaboration-based initiative involving prostate cancer (PC) and survivorship researchers/clinicians from three Canadian prostate centers with the goal of identifying and tracking unmet supportive care needs of patients with localized PC and responding to t

TrueNTH (True North) Peer Navigation is a new study that puts trained prostate cancer survivors and caregivers in touch with patients and caregivers looking for support.

Target enrollment is 1000 prospectively enrolled subjects with an initial negative biopsy scheduled for repeat biopsy.

Subjects must have had their negative index prostate biopsy procedure within 30 months of being scheduled for their repeat biopsy.

The purpose of this study is to determine whether the susceptibility of women to environment exposures, and their urinary elimination differ between follicular and luteal phases of menstrual cycle.

This is a Canadian effort to learn more about becoming pregnant and pregnancy outcomes for mother and child when the mother has multiple sclerosis (MS).  This study will allow us to determine whether having MS and/or taking medication to manage MS can affect the outcome of pregnancy (e.g.

The purpose of this study is to determine if there are differences between patients who receive metformin or placebo with respect to the proportion of patients who meet the diagnostic criteria for metabolic syndrome after 18 months of study treatment.