The goal of this clinical research study is to learn if treatment with standard systemic therapy in combination with surgery or radiation therapy is more effective at controlling prostate cancer than standard systemic therapy alone.

The purpose of this study is to assess enzalutamide plus leuprolide in patients with high-risk nonmetastatic prostate cancer progressing after radical prostatectomy or radiotherapy or both.

The purpose of this project is to compare the effects of a group mindfulness treatment versus a group sex education on sexual desire, sexual distress, and sexual pain in breast cancer survivors.  Participants will be randomly assigned to either eight weekly sessions of a group mindfulness-based t

Prostate Cancer Survivorship 360º is a collaboration-based initiative involving prostate cancer (PC) and survivorship researchers/clinicians from three Canadian prostate centers with the goal of identifying and tracking unmet supportive care needs of patients with localized PC and responding to t

The primary purpose of our study is to examine the feasibility of using the ARESTM device to measure sleep parameters of PCa patients who are on ADT. In addition, we will also assess the feasibility of obtaining serial questionnaires from patients.

The purpose of this study is to determine whether the susceptibility of women to environment exposures, and their urinary elimination differ between follicular and luteal phases of menstrual cycle.

This study will maximize identification of women with Lynch Syndrome using an enhanced screening strategy to identify those at risk.

This is a Canadian effort to learn more about becoming pregnant and pregnancy outcomes for mother and child when the mother has multiple sclerosis (MS).  This study will allow us to determine whether having MS and/or taking medication to manage MS can affect the outcome of pregnancy (e.g.

The purpose of this pilot study is to assess the patient acceptability of, adherence to, and satisfaction with the Sexual Health Rehabilitation Action Plan (SHRAP).  The objective of the SHRAP is to assisst patients/couples in their pathway to sexual health adaptation after prostate cancer treatm

The purpose of this study is to determine if there are differences between patients who receive metformin or placebo with respect to the proportion of patients who meet the diagnostic criteria for metabolic syndrome after 18 months of study treatment.

The purpose if this study is to identify risk factors associated with the development of cardiovascular disease in men with prostate cancer.

The purpose of this study is to document the course of advanced prostate cancer in Canada in terms of disease progression, real-world treatment, and patient management.

This study investigates the use of eye tracking technology as a diagnostic tool for mild traumatic brain injury (mTBI) and concussion. We are looking at the effect of additional working memory (short-term memory) load on the smoothness of eye movements in both concussed and healthy populations.

In this study, we will examine the role of sexual motivation or sexuals goals and their impact on women's sexual well-being.  We will also examine the impact that sexual motivation has on visual attention to erotic and neutral content.  Specifically, we are interested in how these factors are rel

The purpose of this study is to evaluate the prevalence of 4 or more DNA-repair defects in a population of men with metastatic Prostate Cancer (PC) and to use the variants reported to assess biomarker eligibility for niraparib interventional studies.

Prostatitis is so widespread a disease that affects people from youths to seniors, with approximately a third experiencing a remission of symptoms over a year follow-up.

The purpose of this study is to explore different aspects of sexuality by examining how sexual identity is related to visual processing of erotic and neutral images.

The investigators aim to evaluate the feasibility of a larger clinical trial assessing an exercise program during the "teachable moment" in patients with prostate cancer and measuring its effect on tumor apoptosis signaling, lipogenesis and steroidogenesis.

Indigenous women's wellness has multigenerational impacts on the health of indigenous communities.  VCH Aboriginal Health has identified indigenous women's wellness as a priority, and this research will bring the voice of indigenous women into VCH policy and program development.  These goals incl