To look at the differences in "social cognition"-the ability to look at the interpret the social world and put yourself in someone else's shoes-between people with depression,people with frontotemporal dementia, and healthy controls.

The investigators will conduct a proof-of-concept randomized controlled trial study to provide preliminary evidence of efficacy of a resistance exercise training program for maintaining white matter integrity and improving cognitive function in older adults with vascular cognitive impairment, com

This study investigates the use of eye tracking technology as a diagnostic tool for mild traumatic brain injury (mTBI) and concussion. We are looking at the effect of additional working memory (short-term memory) load on the smoothness of eye movements in both concussed and healthy populations.

The Wellness Monitoring for Major Depressive Disorder (MDD) study is a prospective, longitudinal, observational study aimed at identifying biomarkers of relapse in MDD.

To determine the effects of aerobic exercise on hippocampal volumes and severity of psychotic symptoms in a population of psychosis patients compared to healthy age/gender matched volunteers.

tDCS (transcranial Direct Current Stimulation) is a brain stimulation technique that involves passing a very low current through the scalp to change the excitability of underlying brain regions. Moreover, yoga and meditation have recently gained popularity for their proposed health benefits.

The purpose of this study is to determine the clinical, cognitive, motor, brain imaging, genetic and biochemical biomarker characteristics of Alzheimer disease (AD), subcortical vascular disease (SVaD) and mixed dementia (AD + sVaD).

The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid (protein that forms plaques in the brains of people with Alzheimer Disease [AD]).

Losing the ability to walk can lead to fewer opportunities to socialize with friends and family, and participate in the community. When this happens, powered wheelchairs can provide access to homes and communities, contributing to health and well-being.

The purpose of this project is to conduct a proof of concept study in patients with probable Alzheimer's Disease who have mild to moderate hypertension, in order to determine if there is less global brain atrophy over one year, as measured by ventricular enlargement as a primary outcome measure,

The primary objective of the study is to evaluate the efficacy of monthly doses of aducanumab in slowing cognitive and functional impairment as measured by changes in the Clinical Dementia Rating-Sum of Boxes (CDR-SB) score as compared with placebo in participants with early AD.

The CCNA COMPASS-ND study aims to investigate the bases, commonalitites, and distinguishing characteristics of Alzheimer disease and related neurodegenerative disorders. 

recruitment poster

The proposed SYNERGIC trial is uniquely designed to evaluate the effect of aerobic and progressive resistance training exercises, combined with cognitive training and Vitamin D3 supplementation, in cognition and mobility in older adults with Mild Cognitive Impairment (MCI).

The purpose of this study is to determine whether various exercise programs are able to combat cognitive decline.  These include an aerobic training exercise program, a resistance training exercise program, a combination exercise program of aerobic and resistance training, and a balance and tone

The objectives of this 15-day study are:

Current Canadian Clinical Practice guidelines emphasize the need for effective psychosocial adjuncts to pharmacotherapy for schizophrenia (Canadian Psychiatric Association 2005).