Comparison of Aripiprazole Versus Risperidone on Brain Morphology Using MRI (CARB)Significant changes in brain morphology are observed in people with first-episode psychosis. Studies have shown that total brain volume and particular brain structures are decreased in people with psychosis disorders.Recruiting Principal Investigator Alasdair BarrBody Locations and Systems Bipolar DisorderArea VancouverAge 12 and above
Study of the Efficacy of Lurasidone in Cognitive Functioning in Bipolar Patients (ELICE_BD)This is a randomized, double-blind, placebo-controlled, multicentre, parallel-group study to assess the cognitive effects of lurasidone in bipolar I and II patients (manic depression) who are in remission from an episode.Recruiting Principal Investigator Lakshmi N. YathamBody Locations and Systems Bipolar Disorder, Men's and Women's HealthArea VancouverAge 19-65
Efficacy of Convulsive Therapies for Bipolar Depression (CORRECT-BD)The purpose of this study is to assess the efficacy and tolerability of Magnetic Seizure Therapy (MST) as an alternative to electroconvulsive therapy (ECT) for Bipolar Disorder (BD). Recruiting Principal Investigator Fidel Vila-RodriguezBody Locations and Systems Bipolar Disorder, DepressionArea VancouverAge 18 and above
Neuropsychology and treatment response in depressionThis study aims to assess whether initial neuropsychological functioning and early changes in emotional processing in depressed adults correlates with symptom response to medications.Recruiting Principal Investigator Ivan TorresBody Locations and Systems DepressionArea VancouverAge 18-65
Assessing the Role of Cariprazine in Improving Cognition in Euthymic Bipolar Patients (CARPZ-01)The purpose of this study is to examine the efficacy of the drug Cariprazine (VRAYLAR®) in improving cognition in patients with bipolar disorder. Recruiting Principal Investigator Lakshmi N. YathamArea VancouverAge 19 to 65
Mood Stabilizer (MS)+ Antidepressant vs MS + Placebo in Maintenance of Bipolar DisorderPatients with bipolar I disorder (BD) experience depression 3 times more frequently than mania, and antidepressants are prescribed as adjuncts to mood stabilizers in up to 70% of patients.Closed for Recruitment Principal Investigator Lakshmi N. YathamBody Locations and Systems Bipolar DisorderArea VancouverAge 18-70
Bipolar Depression and the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS)The purpose of this study is to assess the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS), a non-invasive (does not enter the body) technique in improving depressive symptoms.Closed for Recruitment Principal Investigator Lakshmi N. YathamBody Locations and Systems Bipolar Disorder, DepressionArea VancouverAge 18-70
